Ontology highlight
ABSTRACT:
SUBMITTER: Liao YT
PROVIDER: S-EPMC6627115 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Liao Yen-Te YT Salvador Alexandra A Harden Leslie A LA Liu Fang F Lavenburg Valerie M VM Li Robert W RW Wu Vivian C H VCH
Antibiotics (Basel, Switzerland) 20190605 2
Shiga toxin-producing <i>Escherichia coli</i> (STEC) O145 is one of the most prevalent non-O157 serogroups associated with foodborne outbreaks. Lytic phages are a potential alternative to antibiotics in combatting bacterial pathogens. In this study, we characterized a <i>Siphoviridae</i> phage lytic against STEC O145 strains as a novel antimicrobial agent. <i>Escherichia</i> phage vB_EcoS-Ro145clw (Ro145clw) was isolated and purified prior to physiological and genomic characterization. Then, in ...[more]