Nuclear Phosphoinositides: Their Regulation and Roles in Nuclear Functions.
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ABSTRACT:
SUBMITTER: Fiume R
PROVIDER: S-EPMC6627530 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Publications
Nuclear Phosphoinositides: Their Regulation and Roles in Nuclear Functions.
Fiume R R Faenza I I Sheth B B Poli A A Vidalle M C MC Mazzetti C C Abdul S H SH Campagnoli F F Fabbrini M M Kimber S T ST Mariani G A GA Xian J J Marvi M V MV Mongiorgi S S Shah Z Z Divecha N N
International journal of molecular sciences 20190619 12
Polyphosphoinositides (PPIns) are a family of seven lipid messengers that regulate a vast array of signalling pathways to control cell proliferation, migration, survival and differentiation. PPIns are differentially present in various sub-cellular compartments and, through the recruitment and regulation of specific proteins, are key regulators of compartment identity and function. Phosphoinositides and the enzymes that synthesise and degrade them are also present in the nuclear membrane and in n ...[more]
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