Ontology highlight
ABSTRACT:
SUBMITTER: Dougan J
PROVIDER: S-EPMC6627806 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Dougan Jodi J Hawsawi Ohuod O Burton Liza J LJ Edwards Gabrielle G Jones Kia K Zou Jin J Nagappan Peri P Wang Guangdi G Zhang Qiang Q Danaher Alira A Bowen Nathan N Hinton Cimona C Odero-Marah Valerie A VA
International journal of molecular sciences 20190621 12
Peroxidasin (PXDN), a human homolog of <i>Drosophila</i> PXDN, belongs to the family of heme peroxidases and has been found to promote oxidative stress in cardiovascular tissue, however, its role in prostate cancer has not been previously elucidated. We hypothesized that PXDN promotes prostate cancer progression via regulation of metabolic and oxidative stress pathways. We analyzed PXDN expression in prostate tissue by immunohistochemistry and found increased PXDN expression with prostate cancer ...[more]