Terminomics Methodologies and the Completeness of Reductive Dimethylation: A Meta-Analysis of Publicly Available Datasets.
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ABSTRACT:
SUBMITTER: Hurtado Silva M
PROVIDER: S-EPMC6631386 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Publications
Terminomics Methodologies and the Completeness of Reductive Dimethylation: A Meta-Analysis of Publicly Available Datasets.
Hurtado Silva Mariella M Berry Iain J IJ Strange Natalie N Djordjevic Steven P SP Padula Matthew P MP
Proteomes 20190329 2
Methods for analyzing the terminal sequences of proteins have been refined over the previous decade; however, few studies have evaluated the quality of the data that have been produced from those methodologies. While performing global N-terminal labelling on bacteria, we observed that the labelling was not complete and investigated whether this was a common occurrence. We assessed the completeness of labelling in a selection of existing, publicly available N-terminomics datasets and empirically ...[more]
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