The association of 6 variants of 8q24 and the risk of glioma: A meta-analysis.
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ABSTRACT:
SUBMITTER: Tong Y
PROVIDER: S-EPMC6635291 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
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The association of 6 variants of 8q24 and the risk of glioma: A meta-analysis.
Tong Yu Y Ye Lv L Li Shiping S Zhao Fengyan F Ying Junjie J Qu Yi Y Li Jinhui J Mu Dezhi D
Medicine 20190701 27
With the advances in sequencing technologies and genome-wide association studies (GWAS), several inherited variants that increase glioma risk have been identified. Ten studies including 8818 cases and 17,551 controls were collected to conduct a meta-analysis to evaluate the associations between 6 variants in 8q24 and glioma risk. Of the 6 variants located in 8q24, 2 have strong significant associations with the risk of glioma, including rs4295627 (P = .003, odds ratio [OR] = 1.21), rs55705857 (P ...[more]
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