Ontology highlight
ABSTRACT:
SUBMITTER: Argyropoulos GP
PROVIDER: S-EPMC6639076 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Argyropoulos Georgios Pd GP Loane Clare C Roca-Fernandez Adriana A Lage-Martinez Carmen C Gurau Oana O Irani Sarosh R SR Butler Christopher R CR
eLife 20190708
Patients with hippocampal amnesia play a central role in memory neuroscience but the neural underpinnings of amnesia are hotly debated. We hypothesized that focal hippocampal damage is associated with changes across the extended hippocampal system and that these, rather than hippocampal atrophy per se, would explain variability in memory between patients. We assessed this hypothesis in a uniquely large cohort of patients (n = 38) after autoimmune limbic encephalitis, a syndrome associated with f ...[more]