Ontology highlight
ABSTRACT:
SUBMITTER: Cheng X
PROVIDER: S-EPMC6639381 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Cheng Xiyue X Pei Pei P Yu Juan J Zhang Qin Q Li Dan D Xie Xiaolu X Wu Jianxin J Wang Shan S Zhang Ting T
Cell death & disease 20190718 8
Retinoic acid (RA), an active derivative of vitamin A, is critical for the neural system development. During the neural development, the RA/RA receptor (RAR) pathway suppresses BMP signaling-mediated proliferation and differentiation of neural progenitor cells. However, how the stability of RAR is regulated during neural system development and how BMP pathway genes expression in neural tissue from human fetuses affected with neural tube defects (NTDs) remain elusive. Here, we report that FBXO30 ...[more]