Ontology highlight
ABSTRACT:
SUBMITTER: Morrow M
PROVIDER: S-EPMC6639595 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Morrow Mary M MaWhinney Samantha S Coyle Ryan P RP Coleman Stacey S SS Gardner Edward M EM Zheng Jia-Hua JH Ellison Lucas L Bushman Lane R LR Kiser Jennifer J JJ Anderson Peter L PL Castillo-Mancilla Jose R JR
The Journal of infectious diseases 20190701 4
<h4>Background</h4>Tenofovir diphosphate (TFV-DP) in dried blood spots (DBS) is associated with viral suppression in persons living with HIV (PLWH) taking tenofovir disoproxil fumarate (TDF). However, its value as a predictor of future viremia remained unknown.<h4>Methods</h4>Blood for plasma viral load (VL) and TFV-DP in DBS were collected (up to 3 visits within 48 weeks) in PLWH on TDF. TFV-DP cut points were selected using logistic prediction models maximizing the area under the receiver oper ...[more]