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Searching the Theoretical Ultimate Limits of Probing Surface-Enhanced Raman Optical Activity.

ABSTRACT: The single-molecule Raman detection has been realized for a long time because of the enhancement effect of surface plasmons. However, the small cross section of Raman optical activity (ROA) makes it so hard to detect the ROA of even a few molecules; and a normal surface-enhanced ROA (SE-ROA) is also very time consumable even with strong laser power. Detecting ROA in an economic way is an important issue. In this paper, we discuss the ultimate limit of the SE-ROA and provide the enhancement factor formula for SE-ROA. Following the formula, we proposed a structure with both huge Raman enhancement and ROA enhancement, which is helpful for single-molecule ROA detection.

SUBMITTER: Hu L

PROVIDER: S-EPMC6641311 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature

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Searching the Theoretical Ultimate Limits of Probing Surface-Enhanced Raman Optical Activity.

Hu Li L Xi Feng F Qv Linhong L Fang Yurui Y

ACS omega 20180129 1

The single-molecule Raman detection has been realized for a long time because of the enhancement effect of surface plasmons. However, the small cross section of Raman optical activity (ROA) makes it so hard to detect the ROA of even a few molecules; and a normal surface-enhanced ROA (SE-ROA) is also very time consumable even with strong laser power. Detecting ROA in an economic way is an important issue. In this paper, we discuss the ultimate limit of the SE-ROA and provide the enhancement facto ...[more]

PMID: 31457959

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