Ontology highlight
ABSTRACT: Background
The role of fruit and vegetables (FVs) consumption in decreasing gallstone disease risk remains contradictory. We performed a meta-analysis to analyze this potential correlation, followed by investigation of dose-response relationship of FVs consumption with gallstone disease.Materials and methods
PubMed, Embase, as well as Web of Science were searched to determine all published researches about the connection of FVs consumption with gallstone disease before March 2018. Relative risks (RRs) or odds ratios (ORs) along with corresponding 95% confidence intervals (CIs) was pooled utilizing random effect models, aiming at examining the correlation of FVs consumption with gallstone disease risk.Results
One cross-sectional study, our case-control studies as well as nine cohort studies were enrolled, covering approximately 33,983 patients with gallstone disease and 1,53,3752 participants. In a pooled analysis, vegetables consumption was significantly related to a decreased gallstone disease risk, (RR?=?0.83, 95% CI, 0.74-0.94, I?=?91.1%), and for fruits consumption, RR was similar (RR?=?0.88, 95%CI, 0.83-0.92, I?=?0.01%). This inverse correlation of FVs consumption with gallstone disease risk was solid in most subgroup analysis. The nonlinear dose-response correlation indicated that gallstone risk was reduced by 4% (RR?=?0.96, 95%CI, 0.93-0.98) and 3% (RR?=?0.97, 95%CI, 0.96-0.98) for every 200?g per day increment in vegetables consumption (P?=?.001) and fruits consumption (P?=?.001), respectively.Conclusion
This study suggests vegetables and fruits consumption is correlated with a significantly reduced risk of gallstone disease.
SUBMITTER: Zhang JW
PROVIDER: S-EPMC6641782 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Zhang Jun-Wei JW Xiong Jian-Ping JP Xu Wei-Yu WY Sang Xin-Ting XT Huang Han-Chun HC Bian Jin J Xu Yi-Yao YY Lu Xin X Zhao Hai-Tao HT
Medicine 20190701 28
<h4>Background</h4>The role of fruit and vegetables (FVs) consumption in decreasing gallstone disease risk remains contradictory. We performed a meta-analysis to analyze this potential correlation, followed by investigation of dose-response relationship of FVs consumption with gallstone disease.<h4>Materials and methods</h4>PubMed, Embase, as well as Web of Science were searched to determine all published researches about the connection of FVs consumption with gallstone disease before March 2018 ...[more]