Dataset Information

Fruits and vegetables consumption and the risk of gallstone diasease: A systematic review and meta-analysis.

ABSTRACT:

Background

The role of fruit and vegetables (FVs) consumption in decreasing gallstone disease risk remains contradictory. We performed a meta-analysis to analyze this potential correlation, followed by investigation of dose-response relationship of FVs consumption with gallstone disease.

Materials and methods

PubMed, Embase, as well as Web of Science were searched to determine all published researches about the connection of FVs consumption with gallstone disease before March 2018. Relative risks (RRs) or odds ratios (ORs) along with corresponding 95% confidence intervals (CIs) was pooled utilizing random effect models, aiming at examining the correlation of FVs consumption with gallstone disease risk.

Results

One cross-sectional study, our case-control studies as well as nine cohort studies were enrolled, covering approximately 33,983 patients with gallstone disease and 1,53,3752 participants. In a pooled analysis, vegetables consumption was significantly related to a decreased gallstone disease risk, (RR?=?0.83, 95% CI, 0.74-0.94, I?=?91.1%), and for fruits consumption, RR was similar (RR?=?0.88, 95%CI, 0.83-0.92, I?=?0.01%). This inverse correlation of FVs consumption with gallstone disease risk was solid in most subgroup analysis. The nonlinear dose-response correlation indicated that gallstone risk was reduced by 4% (RR?=?0.96, 95%CI, 0.93-0.98) and 3% (RR?=?0.97, 95%CI, 0.96-0.98) for every 200?g per day increment in vegetables consumption (P?=?.001) and fruits consumption (P?=?.001), respectively.

Conclusion

This study suggests vegetables and fruits consumption is correlated with a significantly reduced risk of gallstone disease.

SUBMITTER: Zhang JW

PROVIDER: S-EPMC6641782 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Fruits and vegetables consumption and the risk of gallstone diasease: A systematic review and meta-analysis.

Zhang Jun-Wei JW Xiong Jian-Ping JP Xu Wei-Yu WY Sang Xin-Ting XT Huang Han-Chun HC Bian Jin J Xu Yi-Yao YY Lu Xin X Zhao Hai-Tao HT

Medicine 20190701 28

<h4>Background</h4>The role of fruit and vegetables (FVs) consumption in decreasing gallstone disease risk remains contradictory. We performed a meta-analysis to analyze this potential correlation, followed by investigation of dose-response relationship of FVs consumption with gallstone disease.<h4>Materials and methods</h4>PubMed, Embase, as well as Web of Science were searched to determine all published researches about the connection of FVs consumption with gallstone disease before March 2018 ...[more]

PMID: 31305451

Similar Datasets

Project description:Dairy product consumption may affect the risk of hip fracture, but previous studies have reported inconsistent findings. The primary aim of our meta-analysis was to examine and quantify the potential association of dairy product consumption with risk of hip fracture.We searched the databases of PubMed and EMBASE for relevant articles from their inception through April 17, 2017. The final analysis included 10 cohort studies and 8 case-control studies. Random-effects models were used to estimate the pooled risk. Subgroup and dose-response analyses were conducted to explore the relationships between the consumption of milk and the risk of hip fracture.After pooling the data from the included studies, the summary relative risk (RR) for hip fracture for highest versus lowest consumption were 0.91 (95% CI: 0.74-1.12), 0.75 (95% CI: 0.66-0.86), 0.68 (95% CI: 0.61-0. 77), 1.02 (95% CI: 0.93-1.12) for milk, yogurt, cheese, and total dairy products in cohort studies, respectively. Higher milk consumption [Odds ratio (OR), 0.71, 95% CI: 0.55-0. 91] was associated with lower risk of hip fracture for highest versus lowest consumption in case-control studies. After quantifying the specific dose of milk, the summary RR/OR for an increased milk consumption of 200 g/day was 1.00 (95% CI: 0.94-1.07), and 0.89 (95%CI: 0.64-1.24) with significant heterogeneity for cohort and case-control studies, respectively; There was a nonlinear association between milk consumption and hip fracture risk in cohort, and case-control studies.Our findings indicate that consumption of yogurt and cheese was associated with lower risk of hip fracture in cohort studies. However, the consumption of total dairy products and cream was not significantly associated with the risk of hip fracture. There was insufficient evidence to deduce the association between milk consumption and risk of hip fracture. A lower threshold of 200 g/day milk intake may have beneficial effects, whereas the effects of a higher threshold of milk intake are unclear.

Dataset Information

Fruits and vegetables consumption and the risk of gallstone diasease: A systematic review and meta-analysis.

Background

Materials and methods

Results

Conclusion

Publications

Fruits and vegetables consumption and the risk of gallstone diasease: A systematic review and meta-analysis.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure