Ancient origins of low lean mass among South Asians and implications for modern type 2 diabetes susceptibility.
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ABSTRACT:
SUBMITTER: Pomeroy E
PROVIDER: S-EPMC6642207 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Publications
Ancient origins of low lean mass among South Asians and implications for modern type 2 diabetes susceptibility.
Pomeroy Emma E Mushrif-Tripathy Veena V Cole Tim J TJ Wells Jonathan C K JCK Stock Jay T JT
Scientific reports 20190719 1
Living South Asians have low lean tissue mass relative to height, which contributes to their elevated type 2 diabetes susceptibility, particularly when accompanied by obesity. While ongoing lifestyle transitions account for rising obesity, the origins of low lean mass remain unclear. We analysed proxies for lean mass and stature among South Asian skeletons spanning the last 11,000 years (n = 197) to investigate the origins of South Asian low lean mass. Compared with a worldwide sample (n = 2,003 ...[more]
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