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Scientific Advances and New Frontiers in Mesothelioma Therapeutics.


ABSTRACT: Malignant pleural mesothelioma (MPM) is a rare and aggressive cancer that arises from the mesothelial surface of the pleural and peritoneal cavities, the pericardium, and rarely, the tunica vaginalis. The incidence of MPM is expected to increase worldwide in the next two decades. However, even with the use of multimodality treatment, MPM remains challenging to treat, with a 5-year survival rate of less than 5%. The International Association for the Study of Lung Cancer has gathered experts in different areas of mesothelioma research and management to summarize the most significant scientific advances and new frontiers related to mesothelioma therapeutics.

SUBMITTER: Mutti L 

PROVIDER: S-EPMC6643278 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature

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Scientific Advances and New Frontiers in Mesothelioma Therapeutics.

Mutti Luciano L   Peikert Tobias T   Robinson Bruce W S BWS   Scherpereel Arnaud A   Tsao Anne S AS   de Perrot Marc M   Woodard Gavitt A GA   Jablons David M DM   Wiens Jacinta J   Hirsch Fred R FR   Yang Haining H   Carbone Michele M   Thomas Anish A   Hassan Raffit R  

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20180901 9


Malignant pleural mesothelioma (MPM) is a rare and aggressive cancer that arises from the mesothelial surface of the pleural and peritoneal cavities, the pericardium, and rarely, the tunica vaginalis. The incidence of MPM is expected to increase worldwide in the next two decades. However, even with the use of multimodality treatment, MPM remains challenging to treat, with a 5-year survival rate of less than 5%. The International Association for the Study of Lung Cancer has gathered experts in di  ...[more]

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