Ontology highlight
ABSTRACT:
SUBMITTER: Romero-Silva A
PROVIDER: S-EPMC6643617 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Romero-Silva Antonio A Mora-Diez Nelaine N Alvarez-Idaboy J Raul JR
ACS omega 20181204 12
Radicals in biochemical environments can lead to protein damage. Theoretical studies can help us to understand the observed radical selectivity. In this work, the kinetics and thermodynamics of the hydrogen-transfer (HT) and single-electron transfer (SET) reactions between a cysteine derivative and 17 free radicals of biological significance have been theoretically investigated in aqueous and lipid media. With the exception of the reaction with <sup>•</sup>OCCl<sub>3</sub>, all SET reactions in ...[more]