Ontology highlight
ABSTRACT:
SUBMITTER: Mortzfeld BM
PROVIDER: S-EPMC6646324 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Mortzfeld Benedikt M BM Taubenheim Jan J Klimovich Alexander V AV Fraune Sebastian S Rosenstiel Philip P Bosch Thomas C G TCG
Nature communications 20190722 1
How multicellular organisms assess and control their size is a fundamental question in biology, yet the molecular and genetic mechanisms that control organ or organism size remain largely unsolved. The freshwater polyp Hydra demonstrates a high capacity to adapt its body size to different temperatures. Here we identify the molecular mechanisms controlling this phenotypic plasticity and show that temperature-induced cell number changes are controlled by Wnt- and TGF-β signaling. Further we show t ...[more]