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Silicon Industry Waste Polymethylhydrosiloxane-Mediated Benzotriazole Ring Cleavage: A Practical and Green Synthesis of Diverse Benzothiazoles.

ABSTRACT: A green modification has been introduced to the synthesis of benzothiazoles by using polymethylhydrosiloxane (PMHS) for successive steps of benzotriazole ring cleavage and cyclization, an approach which was previously developed in our lab by the use of n-Bu₃SnH. The use of the silicone industry byproduct PMHS makes this protocol a cost-effective and nontoxic one and thus may be considered for the industrial importance.

SUBMITTER: Yadav MS

PROVIDER: S-EPMC6648665 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature

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Silicon Industry Waste Polymethylhydrosiloxane-Mediated Benzotriazole Ring Cleavage: A Practical and Green Synthesis of Diverse Benzothiazoles.

Yadav Mangal S MS Singh Anoop S AS Agrahari Anand K AK Mishra Nidhi N Tiwari Vinod K VK

ACS omega 20190411 4

A green modification has been introduced to the synthesis of benzothiazoles by using polymethylhydrosiloxane (PMHS) for successive steps of benzotriazole ring cleavage and cyclization, an approach which was previously developed in our lab by the use of n-Bu3SnH. The use of the silicone industry byproduct PMHS makes this protocol a cost-effective and nontoxic one and thus may be considered for the industrial importance. ...[more]

PMID: 31459794

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