Dataset Information
Biocatalytic Synthesis of Non-Natural Monoterpene O-Glycosides Exhibiting Superior Antibacterial and Antinematodal Properties.
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ABSTRACT:
SUBMITTER: Bashyal P
PROVIDER: S-EPMC6648847 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Publications
Biocatalytic Synthesis of Non-Natural Monoterpene <i>O</i>-Glycosides Exhibiting Superior Antibacterial and Antinematodal Properties.
ACS omega 20190529 5
A promiscuous <i>Bacillus</i> glycosyltransferase (YjiC) was explored for the enzymatic synthesis of monoterpene <i>O</i>-glycosides in vitro and in vivo. YjiC converted seven monoterpenes into 41 different sugar-conjugated novel glycoside derivatives. The whole-cell biotransformation of the same set of monoterpenes exhibited robust enzyme activity to synthesize <i>O</i>-glucosyl derivatives from <i>Escherichia coli</i>. These newly synthesized selected monoterpene-<i>O</i>-glucosyl derivatives ...[more]