Ontology highlight
ABSTRACT:
SUBMITTER: Tzouras NV
PROVIDER: S-EPMC6648923 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
ACS omega 20190613 6
Tetrasubstituted propargylamines comprise a unique class of highly useful compounds, which can be accessed through the multicomponent coupling between ketones, amines, and alkynes (KA<sup>2</sup> coupling), an underexplored transformation. Herein, the development of a novel, highly efficient, and user-friendly catalytic system for the KA<sup>2</sup> coupling, based on the environmentally benign, inexpensive, and readily available zinc acetate, is described. This system is employed in the multico ...[more]