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One Step Preparation of Peptide-Coated Gold Nanoparticles with Tunable Size.


ABSTRACT: Gold nanoparticles (AuNPs) made from self-assembling peptides have been used in many research fields and attracted a great deal of attention due to their high stability, biocompatibility and functionality. However, existing preparation methods for peptide-coated AuNPs are post-synthesis processes, which are complicated and time consuming. Therefore, a one-step preparation method for peptide-coated AuNPs is proposed here. The AuNPs obtained by this method exhibit good stability. Importantly, peptide-coated AuNPs with precise different sizes can be prepared by this method through pH control of reducing reagent tyrosine in range of 10.0~12.7. Thus, the one-step preparation method proposed here provides a significant tool for the research in different fields concerning NP size, stability and biocompatibility.

SUBMITTER: Jia Y 

PROVIDER: S-EPMC6651442 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature

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One Step Preparation of Peptide-Coated Gold Nanoparticles with Tunable Size.

Jia Yongmei Y   Yan Xiaoning X   Guo Xin X   Zhou Guohua G   Liu Peilian P   Li Zhiguo Z  

Materials (Basel, Switzerland) 20190630 13


Gold nanoparticles (AuNPs) made from self-assembling peptides have been used in many research fields and attracted a great deal of attention due to their high stability, biocompatibility and functionality. However, existing preparation methods for peptide-coated AuNPs are post-synthesis processes, which are complicated and time consuming. Therefore, a one-step preparation method for peptide-coated AuNPs is proposed here. The AuNPs obtained by this method exhibit good stability. Importantly, pept  ...[more]

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