Ontology highlight
ABSTRACT:
SUBMITTER: Xie Z
PROVIDER: S-EPMC6653644 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Xie Zhihui Z Kuhns Douglas B DB Gu Xuesong X Otu Hasan H HH Libermann Towia A TA Gallin John I JI Parikh Samir M SM Druey Kirk M KM
Journal of cellular and molecular medicine 20190618 8
Systemic capillary leak syndrome (SCLS; Clarkson disease) is a rare orphan disorder characterized by transient yet recurrent episodes of hypotension and peripheral oedema due to diffuse vascular leakage of fluids and proteins into soft tissues. Humoral mediators, cellular responses and genetic features accounting for the clinical phenotype of SCLS are virtually unknown. Here, we searched for factors altered in acute SCLS plasma relative to matched convalescent samples using multiplexed aptamer-b ...[more]