Beta-Lactam/Beta-Lactamase Inhibitor Therapy for Potential AmpC-Producing Organisms: A Systematic Review and Meta-Analysis.
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ABSTRACT:
SUBMITTER: Cheng MP
PROVIDER: S-EPMC6656656 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
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Beta-Lactam/Beta-Lactamase Inhibitor Therapy for Potential AmpC-Producing Organisms: A Systematic Review and Meta-Analysis.
Cheng Matthew P MP Lee Robyn S RS Cheng Alexandre P AP De L'étoile-Morel Samuel S Demir Koray K Yansouni Cedric P CP Harris Patrick P Mcdonald Emily G EG Lee Todd C TC
Open forum infectious diseases 20190701 7
The optimal treatment for potential AmpC-producing Enterobacteriaceae, including Serratia, Providencia, Citrobacter, Enterobacter, and Morganella species, remains unknown. An updated systematic review and meta-analysis of studies comparing beta-lactam/beta-lactamase inhibitors with carbapenems in the treatment of bloodstream infections with these pathogens found no significant difference in 30-day mortality (OR, 1.13; 95% CI, 0.58 - 2.20). ...[more]
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