Ontology highlight
ABSTRACT:
SUBMITTER: Bouchal P
PROVIDER: S-EPMC6656695 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Bouchal Pavel P Schubert Olga T OT Faktor Jakub J Capkova Lenka L Imrichova Hana H Zoufalova Karolina K Paralova Vendula V Hrstka Roman R Liu Yansheng Y Ebhardt Holger Alexander HA Budinska Eva E Nenutil Rudolf R Aebersold Ruedi R
Cell reports 20190701 3
Accurate classification of breast tumors is vital for patient management decisions and enables more precise cancer treatment. Here, we present a quantitative proteotyping approach based on sequential windowed acquisition of all theoretical fragment ion spectra (SWATH) mass spectrometry and establish key proteins for breast tumor classification. The study is based on 96 tissue samples representing five conventional breast cancer subtypes. SWATH proteotype patterns largely recapitulate these subty ...[more]