Enhancement of Single Molecule Raman Scattering using Sprouted Potato Shaped Bimetallic Nanoparticles.

ABSTRACT: Herein, for the first time, we report the single molecule surface enhanced resonance Raman scattering (SERRS) and surface enhanced Raman scattering (SERS) spectra with high signal to noise ratio (S/N) using plasmon-active substrates fabricated by sprouted potato shaped Au-Ag bimetallic nanoparticles, prepared using a new one-step synthesis method. This particular shape of the nanoparticles has been obtained by fixing the amount of Au and carefully adjusting the amount of Ag. These nanoparticles have been characterized using scanning electron microscopy, extinction spectroscopy, and glancing angle X-ray diffraction. The single molecule sensitivity of SERS substrates has been tested with two different molecular Raman probes. The origin of the electromagnetic enhancement of single molecule Raman scattering in the presence of sprouted shape nanoparticles has been explained using quasi-static theory as well as finite element method (FEM) simulations. Moreover, the role of (i) methods for binding Raman probe molecules to the substrate, (ii) concentration of molecules, and (iii) Au-Ag ratio on the spectra of molecules has been studied in detail.

SUBMITTER: William RV 

PROVIDER: S-EPMC6656737 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature