FDA-ARGOS is a database with public quality-controlled reference genomes for diagnostic use and regulatory science.
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ABSTRACT:
SUBMITTER: Sichtig H
PROVIDER: S-EPMC6658474 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Publications
FDA-ARGOS is a database with public quality-controlled reference genomes for diagnostic use and regulatory science.
Sichtig Heike H Minogue Timothy T Yan Yi Y Stefan Christopher C Hall Adrienne A Tallon Luke L Sadzewicz Lisa L Nadendla Suvarna S Klimke William W Hatcher Eneida E Shumway Martin M Aldea Dayanara Lebron DL Allen Jonathan J Koehler Jeffrey J Slezak Tom T Lovell Stephen S Schoepp Randal R Scherf Uwe U
Nature communications 20190725 1
FDA proactively invests in tools to support innovation of emerging technologies, such as infectious disease next generation sequencing (ID-NGS). Here, we introduce FDA-ARGOS quality-controlled reference genomes as a public database for diagnostic purposes and demonstrate its utility on the example of two use cases. We provide quality control metrics for the FDA-ARGOS genomic database resource and outline the need for genome quality gap filling in the public domain. In the first use case, we show ...[more]
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