Frontal pathways in cognitive control: direct evidence from intraoperative stimulation and diffusion tractography.

ABSTRACT: A key aspect of cognitive control is the management of conflicting incoming information to achieve a goal, termed 'interference control'. Although the role of the right frontal lobe in interference control is evident, the white matter tracts subserving this cognitive process remain unclear. To investigate this, we studied the effect of transient network disruption (by means of direct electrical stimulation) and permanent disconnection (resulting from neurosurgical resection) on interference control processes, using the Stroop test in the intraoperative and extraoperative neurosurgical setting. We evaluated the sites at which errors could be produced by direct electrical stimulation during an intraoperative Stroop test in 34 patients with frontal right hemisphere glioma. Lesion-symptom mapp

SUBMITTER: Puglisi G 

PROVIDER: S-EPMC6658848 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature