Ontology highlight
ABSTRACT:
SUBMITTER: Zhang RW
PROVIDER: S-EPMC6659749 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Zhang Rong-Wei RW Du Wen-Jie WJ Prober David A DA Du Jiu-Lin JL
Cell reports 20190601 10
Retinal waves, the spontaneous patterned neural activities propagating among developing retinal ganglion cells (RGCs), instruct the activity-dependent refinement of visuotopic maps. Although it is known that the wave is initiated successively by amacrine cells and bipolar cells, the behavior and function of glia in retinal waves remain unclear. Using multiple in vivo methods in larval zebrafish, we found that Müller glial cells (MGCs) display wave-like spontaneous activities, which start at MGC ...[more]