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New neural activity patterns emerge with long-term learning.


ABSTRACT: Learning has been associated with changes in the brain at every level of organization. However, it remains difficult to establish a causal link between specific changes in the brain and new behavioral abilities. We establish that new neural activity patterns emerge with learning. We demonstrate that these new neural activity patterns cause the new behavior. Thus, the formation of new patterns of neural population activity can underlie the learning of new skills.

SUBMITTER: Oby ER 

PROVIDER: S-EPMC6660765 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature

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New neural activity patterns emerge with long-term learning.

Oby Emily R ER   Golub Matthew D MD   Hennig Jay A JA   Degenhart Alan D AD   Tyler-Kabara Elizabeth C EC   Yu Byron M BM   Chase Steven M SM   Batista Aaron P AP  

Proceedings of the National Academy of Sciences of the United States of America 20190610 30


Learning has been associated with changes in the brain at every level of organization. However, it remains difficult to establish a causal link between specific changes in the brain and new behavioral abilities. We establish that new neural activity patterns emerge with learning. We demonstrate that these new neural activity patterns cause the new behavior. Thus, the formation of new patterns of neural population activity can underlie the learning of new skills. ...[more]

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