Ontology highlight
ABSTRACT:
SUBMITTER: Wendte JM
PROVIDER: S-EPMC6663294 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Wendte Jered M JM Wendte Jered M JM Zhang Yinwen Y Ji Lexiang L Shi Xiuling X Hazarika Rashmi R RR Shahryary Yadollah Y Johannes Frank F Schmitz Robert J RJ
eLife 20190729
In many plant species, a subset of transcribed genes are characterized by strictly CG-context DNA methylation, referred to as gene body methylation (gbM). The mechanisms that establish gbM are unclear, yet flowering plant species naturally without gbM lack the DNA methyltransferase, CMT3, which maintains CHG (H = A, C, or T) and not CG methylation at constitutive heterochromatin. Here, we identify the mechanistic basis for gbM establishment by expressing <i>CMT3</i> in a species naturally lackin ...[more]