Ontology highlight
ABSTRACT:
SUBMITTER: Roizen JD
PROVIDER: S-EPMC6663580 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20190221 6
Normal vitamin D homeostasis is critical for optimal health; nevertheless, vitamin D deficiency is a worldwide public health problem. Vitamin D insufficiency is most commonly due to inadequate cutaneous synthesis of cholecalciferol and/or insufficient intake of vitamin D, but can also arise as a consequence of pathological states such as obesity. Serum concentrations of 25(OH)D (calcidiol) are low in obesity, and fail to increase appropriately after vitamin D supplementation. Although sequestrat ...[more]