Ontology highlight
ABSTRACT:
SUBMITTER: Wang Z
PROVIDER: S-EPMC6664040 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Wang Zhilei Z Xu Guang G Gao Yuan Y Zhan Xiaoyan X Qin Nan N Fu Shubin S Li Ruisheng R Niu Ming M Wang Jiabo J Liu Youping Y Xiao Xiaohe X Bai Zhaofang Z
Acta pharmaceutica Sinica. B 20190214 4
Aberrant activation of NLRP3 inflammasome has been implicated in the pathogenesis of diverse inflammation-related diseases, and pharmacological molecules targeting NLRP3 inflammasome are of considerable value to identifying potential therapeutic interventions. Cardamonin (CDN), the major active ingredient of the traditional Chinese medicinal herb <i>Alpinia katsumadai</i>, has exerted an excellent anti-inflammatory activity, but the mechanism underlying this role is not fully understood. Here, w ...[more]