Prophylactic anticonvulsants for gliomas: a seven-year retrospective analysis.

ABSTRACT:

Background

The American Academy of Neurology (AAN) does not recommend routine use of prophylactic antiepileptic drugs (pAEDs) in patients with newly diagnosed brain tumors. If used in the perioperative setting, discontinuation is suggested after the first postoperative week. It is unclear whether such recommendations are followed. Our objective was to compare our perioperative and long-term pAED use in glioma patients with AAN practice parameters.

Methods

Retrospective chart review was performed on 578 glioma patients from 2006 to 2013. Seizures and AED use were assessed at surgery, 3 months postoperatively and death, last visit or 16 months postoperatively. Patients were divided into three groups at surgery: seizure-free with pAED, seizure-free without pAED, and seizure pat

SUBMITTER: Lapointe S 

PROVIDER: S-EPMC6664612 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature