Ontology highlight
ABSTRACT:
SUBMITTER: Ambigapathy G
PROVIDER: S-EPMC6667796 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Ambigapathy Ganesh G Schmit Taylor T Mathur Ram Kumar RK Nookala Suba S Bahri Saad S Pirofski Liise-Anne LA Khan M Nadeem MN
The Journal of infectious diseases 20190701 5
<h4>Background</h4>We sought to determine the role of host interleukin 17A (IL-17A) response against colonizing Streptococcus pneumoniae, and its transition to a pathogen during coinfection with an influenza virus, influenza A H1N1 A/Puerto Rico/8/1934 (PR8).<h4>Method</h4>Wild-type (WT) C57BL/6 mice were intranasally inoculated with S. pneumoniae serotype 6A to establish colonization and later infected with the influenza strain, PR8, resulting in invasive S. pneumoniae disease. The role of the ...[more]