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Biometric recognition of newborns and infants by non-contact fingerprinting: lessons learned.

ABSTRACT: Despite years of effort, reliable biometric identification of newborns and young children has remained elusive. In this paper, we review the importance of trusted identification methods, the biometric landscape for infants and adults, barriers and success stories, and we discuss specific failure modes particular to young children. We then describe our approach to infant identification using non-contact optical imaging of fingerprints. We detail our technology development history, including Human-Centered Design methods, various iterations of our platform, and how these iterations addressed failure modes in the identification process. We close with a brief description of our clinical trial of newborns and infants at an urban hospital in Mexico and report preliminary results that show high accuracy, with matching rates consistent with acceptable field-performance for reliable biometric identification in large populations.

SUBMITTER: Saggese S

PROVIDER: S-EPMC6667827 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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Biometric recognition of newborns and infants by non-contact fingerprinting: lessons learned.

Saggese Steven S Zhao Yunting Y Kalisky Tom T Avery Courtney C Forster Deborah D Edith Duarte-Vera Lilia L Almada-Salazar Lucila Alejandra LA Perales-Gonzalez Daniel D Hubenko Alexandra A Kleeman Michael M Chacon-Cruz Enrique E Aronoff-Spencer Eliah E

Gates open research 20191105

Despite years of effort, reliable biometric identification of newborns and young children has remained elusive. In this paper, we review the importance of trusted identification methods, the biometric landscape for infants and adults, barriers and success stories, and we discuss specific failure modes particular to young children. We then describe our approach to infant identification using non-contact optical imaging of fingerprints. We detail our technology development history, including Human ...[more]

PMID: 31410396

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Project description:Background: Contact tracing is a core element of the public health response to emerging infectious diseases including COVID-19. Better understanding the implementation context of contact tracing for pandemics, including individual- and systems-level predictors of success, is critical to preparing for future epidemics. Methods: We carried out a prospective implementation study of an emergency volunteer contact tracing program established in New Haven, Connecticut between April 4 and May 19, 2020. We assessed the yield and timeliness of case and contact outreach in reference to CDC benchmarks, and identified individual and programmatic predictors of successful implementation using multivariable regression models. We synthesized our findings using the RE-AIM implementation framework. Results: Case investigators interviewed only 826 (48%) of 1,705 cases and were unable to reach 545 (32%) because of incomplete information and 334 (20%) who missed or declined repeated outreach calls. Contact notifiers reached just 687 (28%) of 2,437 reported contacts, and were unable to reach 1,597 (66%) with incomplete information and 153 (6%) who missed or declined repeated outreach calls. The median time-to-case-interview was 5 days and time-to-contact-notification 8 days. However, among notified contacts with complete time data, 457 (71%) were reached within 6 days of exposure. The least likely groups to be interviewed were elderly (adjusted relative risk, aRR 0.74, 95% CI 0.61-0.89, p = 0.012, vs. young adult) and Black/African-American cases (aRR 0.88, 95% CI 0.80-0.97, pairwise p = 0.01, vs. Hispanic/Latinx). However, ties between cases and their contacts strongly influenced contact notification success (Intraclass Correlation Coefficient (ICC) 0.60). Surging caseloads and high volunteer turnover (case investigator n = 144, median time from sign-up to retirement from program was 4 weeks) required the program to supplement the volunteer workforce with paid public health nurses. Conclusions: An emergency volunteer-run contact tracing program fell short of CDC benchmarks for time and yield, largely due to difficulty collecting the information required for outreach to cases and contacts. To improve uptake, contact tracing programs must professionalize the workforce; better integrate testing and tracing services; capitalize on positive social influences between cases and contacts; and address racial and age-related disparities through enhanced community engagement.

Project description:Diffuse white matter injury (dWMI) is a major cause of morbidity in the extremely preterm born infant leading to life-long neurological impairments, including deficits in cognitive, motor, sensory, psychological, and behavioral functioning. At present, no treatment options are clinically available to combat dWMI and therefore exploration of novel strategies is urgently needed. In recent years, the pathophysiology underlying dWMI has slowly started to be unraveled, pointing towards the disturbed maturation of oligodendrocytes (OLs) as a key mechanism. Immature OL precursor cells in the developing brain are believed to be highly sensitive to perinatal inflammation and cerebral oxygen fluctuations, leading to impaired OL differentiation and eventually myelination failure. OL lineage development under normal and pathological circumstances and the process of (re)myelination have been studied extensively over the years, often in the context of other adult and pediatric white matter pathologies such as stroke and multiple sclerosis (MS). Various studies have proposed stem cell-based therapeutic strategies to boost white matter regeneration as a potential strategy against a wide range of neurological diseases. In this review we will discuss experimental studies focusing on mesenchymal stem cell (MSC) therapy to reduce white matter injury (WMI) in multiple adult and neonatal neurological diseases. What lessons have been learned from these previous studies and how can we translate this knowledge to application of MSCs for the injured white matter in the preterm infant? A perspective on the current state of stem cell therapy will be given and we will discuss different important considerations of MSCs including cellular sources, timing of treatment and administration routes. Furthermore, we reflect on optimization strategies that could potentially reinforce stem cell therapy, including preconditioning and genetic engineering of stem cells or using cell-free stem cell products, to optimize cell-based strategy for vulnerable preterm infants in the near future.

Dataset Information

Biometric recognition of newborns and infants by non-contact fingerprinting: lessons learned.

Publications

Biometric recognition of newborns and infants by non-contact fingerprinting: lessons learned.

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