Ontology highlight
ABSTRACT:
SUBMITTER: Musso PY
PROVIDER: S-EPMC6668987 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Musso Pierre-Yves PY Junca Pierre P Jelen Meghan M Feldman-Kiss Damian D Zhang Han H Chan Rachel Cw RC Gordon Michael D MD
eLife 20190719
Manipulating feeding circuits in freely moving animals is challenging, in part because the timing of sensory inputs is affected by the animal's behavior. To address this challenge in <i>Drosophila,</i> we developed the Sip-Triggered Optogenetic Behavior Enclosure ('STROBE'). The STROBE is a closed-looped system for real-time optogenetic activation of feeding flies, designed to evoke neural excitation coincident with food contact. We previously demonstrated the STROBE's utility in probing the val ...[more]