Dataset Information

Dataset on preliminary phytochemical analysis and antioxidant activity of selected invasive alien plant species used in the treatment of sexually transmitted infections in Waterberg district, South Africa.

ABSTRACT: The current dataset follows the published article [1]. The dataset provides preliminary phytochemical analysis and antioxidant activity of selected invasive alien plant used by Bapedi Traditional Health Practitioners to treat sexually transmitted infections (STIs). It was evident that seven STIs are treated with herbal remedies of the documented plant species. Informational on the medicinal plant uses and the use categories of sexually transmitted infections are presented on table 1. Table 2 shows the yield of plant extracts. Detailed data on phytochemical analysis and antioxidant activity are presented on Fig 1 and 2 respectively. Rf values of separated compounds are provided in Table 3. The data contains both qualitative and quantitative information.

SUBMITTER: Maema LP

PROVIDER: S-EPMC6669344 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature

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Dataset on preliminary phytochemical analysis and antioxidant activity of selected invasive alien plant species used in the treatment of sexually transmitted infections in Waterberg district, South Africa.

Maema Lesibana Petrus LP Potgieter Martin Johannes MJ Samie Amidou A

Data in brief 20190717

The current dataset follows the published article [1]. The dataset provides preliminary phytochemical analysis and antioxidant activity of selected invasive alien plant used by Bapedi Traditional Health Practitioners to treat sexually transmitted infections (STIs). It was evident that seven STIs are treated with herbal remedies of the documented plant species. Informational on the medicinal plant uses and the use categories of sexually transmitted infections are presented on table 1. Table 2 sho ...[more]

PMID: 31388524

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Project description:Although orthodox medications are available for skin diseases, expensive dermatological services have necessitated the use of medicinal plants as a cheaper alternative. This study evaluated the pharmacological and phytochemical profiles of four medicinal plants (Drimia sanguinea, Elephantorrhiza elephantina, Helichrysum paronychioides, and Senecio longiflorus) used for treating skin diseases. Petroleum ether and 50% methanol extracts of the plants were screened for antimicrobial activity against six microbes: Bacillus cereus, Shigella flexneri, Candida glabrata, Candida krusei, Trichophyton rubrum and Trichophyton tonsurans using the micro-dilution technique. Antioxidant activity was conducted using 2,2-diphenyl-1-picryhydrazyl (DPPH) free radical scavenging and β-carotene linoleic acid models. Cytotoxicity was determined against African green monkey Vero kidney cells based on the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) colorimetric assay. Spectrophotometric and Gas Chromatography-Mass Spectrometry (GC-MS) methods were used to evaluate the phytochemical constituents. All the extracts demonstrated varying degrees of antimicrobial potencies. Shigella flexneri, Candida glabrata, Trichophyton rubrum and Trichophyton tonsurans were most susceptible at 0.10 mg/mL. In the DPPH test, EC50 values ranged from approximately 6-93 µg/mL and 65%-85% antioxidant activity in the β-carotene linoleic acid antioxidant activity model. The phenolic and flavonoid contents ranged from 3.5-64 mg GAE/g and 1.25-28 mg CE/g DW, respectively. The LC50 values of the cytotoxicity assay ranged from 0.015-5622 µg/mL. GC-MS analysis revealed a rich pool (94-198) of bioactive compounds including dotriacontane, benzothiazole, heptacosane, bumetrizole, phthalic acid, stigmasterol, hexanoic acid and eicosanoic acid, which were common to the four plants. The current findings provide some degree of scientific evidence supporting the use of these four plants in folk medicine. However, the plants with high cytotoxicity need to be used with caution.

Dataset Information

Dataset on preliminary phytochemical analysis and antioxidant activity of selected invasive alien plant species used in the treatment of sexually transmitted infections in Waterberg district, South Africa.

Publications

Dataset on preliminary phytochemical analysis and antioxidant activity of selected invasive alien plant species used in the treatment of sexually transmitted infections in Waterberg district, South Africa.

Similar Datasets

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