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Progress on the Prevention and Treatment of Hantavirus Disease.


ABSTRACT: Hantaviruses, members of the order Bunyavirales, family Hantaviridae, have a world-wide distribution and are responsible for greater than 150,000 cases of disease per year. The spectrum of disease associated with hantavirus infection include hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS) also known as hantavirus cardiopulmonary syndrome (HCPS). There are currently no FDA-approved vaccines or treatments for these hantavirus diseases. This review provides a summary of the status of vaccine and antiviral treatment efforts including those tested in animal models or human clinical trials.

SUBMITTER: Brocato RL 

PROVIDER: S-EPMC6669544 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature

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Progress on the Prevention and Treatment of Hantavirus Disease.

Brocato Rebecca L RL   Hooper Jay W JW  

Viruses 20190704 7


Hantaviruses, members of the order <i>Bunyavirales</i>, family <i>Hantaviridae</i>, have a world-wide distribution and are responsible for greater than 150,000 cases of disease per year. The spectrum of disease associated with hantavirus infection include hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS) also known as hantavirus cardiopulmonary syndrome (HCPS). There are currently no FDA-approved vaccines or treatments for these hantavirus diseases. This review  ...[more]

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