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A miniaturized spectrometer for NMR relaxometry under extreme conditions.

ABSTRACT: With the advent of integrated electronics, microfabrication and novel chemistry, NMR (Nuclear Magnetic Resonance) methods, embodied in miniaturized spectrometers, have found profound uses in recent years that are beyond their conventional niche. In this work, we extend NMR relaxometry on a minute sample below 20??L to challenging environment of 150?°C in temperature and 900?bar in pressure. Combined with a single-board NMR spectrometer, we further demonstrate multidimensional NMR relaxometries capable of resolving compositions of complex fluids. The confluence of HTHP (high-pressure high-temperature) capability, minimal sample volume, and reduced sensor envelop and power budget creates a new class of mobile NMR platforms, bringing the powerful analytical toolkit in a miniaturized footprint to extreme operating conditions.

SUBMITTER: Tang Y

PROVIDER: S-EPMC6673705 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature

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A miniaturized spectrometer for NMR relaxometry under extreme conditions.

Tang Yiqiao Y McCowan David D Song Yi-Qiao YQ

Scientific reports 20190801 1

With the advent of integrated electronics, microfabrication and novel chemistry, NMR (Nuclear Magnetic Resonance) methods, embodied in miniaturized spectrometers, have found profound uses in recent years that are beyond their conventional niche. In this work, we extend NMR relaxometry on a minute sample below 20 μL to challenging environment of 150 °C in temperature and 900 bar in pressure. Combined with a single-board NMR spectrometer, we further demonstrate multidimensional NMR relaxometries c ...[more]

PMID: 31371756

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