Ontology highlight
ABSTRACT:
SUBMITTER: Brockschnieder D
PROVIDER: S-EPMC6675369 | biostudies-literature | 2006 Jan
REPOSITORIES: biostudies-literature
Brockschnieder Damian D Sabanay Helena H Riethmacher Dieter D Peles Elior E
The Journal of neuroscience : the official journal of the Society for Neuroscience 20060101 3
Oligodendrocytes form an insulating multilamellar structure of compact myelin around axons, thereby allowing rapid propagation of action potentials. Despite the considerable clinical importance of myelination, little is known about the molecular mechanisms that enable oligodendrocytes to generate their specialized membrane wrapping. Here, we used microarray expression profiling of oligodendrocyte-ablated mutant mice to identify new glial molecules that are involved in CNS myelination. This effor ...[more]