Ontology highlight
ABSTRACT:
SUBMITTER: Bageritz J
PROVIDER: S-EPMC6675608 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Bageritz Josephine J Willnow Philipp P Valentini Erica E Leible Svenja S Boutros Michael M Teleman Aurelio A AA
Nature methods 20190729 8
The Drosophila wing disc has been a fundamental model system for the discovery of key signaling pathways and for our understanding of developmental processes. However, a complete map of gene expression in this tissue is lacking. To obtain a gene expression atlas in the wing disc, we employed single cell RNA sequencing (scRNA-seq) and developed a method for analyzing scRNA-seq data based on gene expression correlations rather than cell mapping. This enables us to compute expression maps for all d ...[more]