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In-Hospital mortality varies by procedure type among cirrhosis surgery admissions.


ABSTRACT: BACKGROUND:Patients with cirrhosis have increased peri-operative mortality risk relative to non-cirrhotic patients, however, the impact of surgical procedure category on this risk is poorly understood. METHODS:We performed a retrospective cohort study of cirrhosis surgery admissions using the National Inpatient Sample between 2012 and 2014 to estimate the adjusted odds of in-hospital mortality by surgical procedure category. RESULTS:In-hospital mortality differed by surgical procedure category. Relative to major orthopedic surgeries, major abdominal surgeries had the highest odds of in-hospital mortality (odds ratio [OR] 8.27, 95% confidence interval [CI] 5.96-11.49), followed by major cardiovascular surgeries (OR 3.45, 95% CI 2.33-5.09). There was also a significant interaction term, whereby elective/non-elective admission status impacted in-hospital mortality risk differently for each surgical procedure category (P < 0.001). CONCLUSION:In-hospital mortality varies substantially by surgical procedure type. Accounting for procedure type in models may improve risk prediction for peri-operative mortality in patients with cirrhosis.

SUBMITTER: Mahmud N 

PROVIDER: S-EPMC6675652 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature

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In-Hospital mortality varies by procedure type among cirrhosis surgery admissions.

Mahmud Nadim N   Fricker Zachary Z   Serper Marina M   Kaplan David E DE   Rothstein Kenneth D KD   Goldberg David S DS  

Liver international : official journal of the International Association for the Study of the Liver 20190617 8


<h4>Background</h4>Patients with cirrhosis have increased peri-operative mortality risk relative to non-cirrhotic patients, however, the impact of surgical procedure category on this risk is poorly understood.<h4>Methods</h4>We performed a retrospective cohort study of cirrhosis surgery admissions using the National Inpatient Sample between 2012 and 2014 to estimate the adjusted odds of in-hospital mortality by surgical procedure category.<h4>Results</h4>In-hospital mortality differed by surgica  ...[more]

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