Ontology highlight
ABSTRACT:
SUBMITTER: Hong CS
PROVIDER: S-EPMC6677151 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Hong Chang-Soo CS Park Mi-Ra MR Sun Eun-Gene EG Choi Wonyoung W Hwang Jun-Eul JE Bae Woo-Kyun WK Rhee Joon Haeng JH Cho Sang-Hee SH Chung Ik-Joo IJ
Frontiers in immunology 20190726
Galectin-3-binding protein (Gal-3BP) is a member of the family of scavenger receptor cysteine-rich (SRCR) domain-containing proteins, which are associated with the immune system. However, the functional roles and signaling mechanisms of Gal-3BP in host defense and the immune response remain largely unknown. Here, we identified cellular Gal-3BP as a negative regulator of NF-κB activation and proinflammatory cytokine production in lipopolysaccharide (LPS)-stimulated murine embryonic fibroblasts (M ...[more]