DNA fragility in the parallel evolution of pelvic reduction in stickleback fish.
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ABSTRACT:
SUBMITTER: Xie KT
PROVIDER: S-EPMC6677656 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Publications
DNA fragility in the parallel evolution of pelvic reduction in stickleback fish.
Xie Kathleen T KT Wang Guliang G Thompson Abbey C AC Wucherpfennig Julia I JI Reimchen Thomas E TE MacColl Andrew D C ADC Schluter Dolph D Bell Michael A MA Vasquez Karen M KM Kingsley David M DM
Science (New York, N.Y.) 20190103 6422
Evolution generates a remarkable breadth of living forms, but many traits evolve repeatedly, by mechanisms that are still poorly understood. A classic example of repeated evolution is the loss of pelvic hindfins in stickleback fish (<i>Gasterosteus aculeatus</i>). Repeated pelvic loss maps to recurrent deletions of a pelvic enhancer of the <i>Pitx1</i> gene. Here, we identify molecular features contributing to these recurrent deletions. <i>Pitx1</i> enhancer sequences form alternative DNA struct ...[more]
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