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Somatostatin receptor 2 targeting in small cell lung carcinoma: perspectives.


ABSTRACT: Small Cell lung carcinoma (SCLC) is the most lethal and aggressive subtype of lung cancer. Novel targeting approaches and agents are desperately needed. In this perspectives, we briefly explore recent data published in the International Journal of Cancer suggesting Somatostatin Receptor 2 (SSTR2) as a viable target for SCLC, summarize the current clinical trial space, and describe promising new research and clinical directions for Somatostatin Receptor 2 targeting in SCLC.

SUBMITTER: Lehman JM 

PROVIDER: S-EPMC6677662 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature

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Somatostatin receptor 2 targeting in small cell lung carcinoma: perspectives.

Lehman Jonathan M JM   aMassion Pierre P PP  

Oncotarget 20190730 46


Small Cell lung carcinoma (SCLC) is the most lethal and aggressive subtype of lung cancer. Novel targeting approaches and agents are desperately needed. In this perspectives, we briefly explore recent data published in the International Journal of Cancer suggesting Somatostatin Receptor 2 (SSTR2) as a viable target for SCLC, summarize the current clinical trial space, and describe promising new research and clinical directions for Somatostatin Receptor 2 targeting in SCLC. ...[more]

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