Ontology highlight
ABSTRACT:
SUBMITTER: Satav T
PROVIDER: S-EPMC6680354 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Satav Tushar T Korevaar Peter P de Greef Tom F A TF Huskens Jurriaan J Jonkheijm Pascal P
Chemistry (Weinheim an der Bergstrasse, Germany) 20160729 36
The modulation of the hierarchical nucleated self-assembly of tri-β(3) -peptides has been studied. β(3) -Tyrosine provided a handle to control the assembly process through host-guest interactions with CB[7] and CB[8]. By varying the cavity size from CB[7] to CB[8] distinct phases of assembling tri-β(3) -peptides were arrested. Given the limited size of the CB[7] cavity, only one aromatic β(3) -tyrosine can be simultaneously hosted and, hence, CB[7] was primarily acting as an inhibitor of self-as ...[more]