Ontology highlight
ABSTRACT:
SUBMITTER: Marson D
PROVIDER: S-EPMC6680565 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Marson Domenico D Laurini Erik E Aulic Suzana S Fermeglia Maurizio M Pricl Sabrina S
Pharmaceutics 20190718 7
Small interfering RNAs (siRNAs) represent a new approach towards the inhibition of gene expression; as such, they have rapidly emerged as promising therapeutics for a plethora of important human pathologies including cancer, cardiovascular diseases, and other disorders of a genetic etiology. However, the clinical translation of RNA interference (RNAi) requires safe and efficient vectors for siRNA delivery into cells. Dendrimers are attractive nanovectors to serve this purpose, as they present a ...[more]