Ontology highlight
ABSTRACT:
SUBMITTER: Shen L
PROVIDER: S-EPMC6681357 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Shen Linyuan L Tan Zhendong Z Gan Mailin M Li Qiang Q Chen Lei L Niu Lili L Jiang Dongmei D Zhao Ye Y Wang Jinyong J Li Xuewei X Zhang Shunhua S Zhu Li L
Biomolecules 20190711 7
tRNA-derived fragments (tRFs), a novel type of non-coding RNA derived from tRNAs, play an important part in governing gene expressions at a post-transcriptional level. To date, the regulatory mechanism of tRFs governing fat deposition and adipogenesis is completely unknown. In this study, high fat diet was employed to induce an obese rat model, and tRFs transcriptome sequencing was conducted to identify differentially expressed tRFs that response to obesity. We found out that tRF<sup>GluTTC</sup ...[more]