Ontology highlight
ABSTRACT:
SUBMITTER: Singh A
PROVIDER: S-EPMC6682034 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Singh Atamjit A Singh Jatinder Vir JV Rana Abhineet A Bhagat Kavita K Gulati Harmandeep Kaur HK Kumar Raman R Salwan Rajan R Bhagat Kajal K Kaur Gurinder G Singh Navjot N Kumar Randeep R Singh Harbinder H Sharma Sahil S Bedi Preet Mohinder Singh PMS
ACS omega 20190705 7
Keeping in view various pharmacological attributes of curcumin, coumarin, and isatin derivatives, triazole-tethered monocarbonyl curcumin-coumarin and curcumin-isatin molecular hybrids have been synthesized and evaluated for their antibacterial potential against Gram-positive (<i>Enterococcus faecalis</i> and <i>Staphylococcus aureus</i>) and Gram-negative (<i>Pseudomonas aeruginosa</i> and <i>Escherichia coli</i>) human pathogenic bacterial strains. Among all hybrid molecules, <b>A-4</b> and <b ...[more]