Dataset Information

Macromolecular Probe Based on a NiII/TbIII Coordination Polymer for Sensitive Recognition of Human Serum Albumin (HSA) and MnO4.

ABSTRACT: Reported here are the design and fluorescence characters of a NiII/TbIII polymer, [Tb2Ni3(HCAM)6(H2O)12] n (1) (H3CAM = chelidamic acid). Under physiological conditions, the binding of biocompatible water soluble 1 to human serum albumin (HSA) was studied by spectroscopy techniques, which revealed that 1 could inherent the fluorescent light of HSA in a static quencher course and change the HSA second-level structure. The marked enhancement in 1 and its fluorescence intensity provide conclusive evidence that 1 can play the role of a "turn-on" sensor for recognition and detection of HSA in other biological interferents with a K sv value of 7.68 × 104 M-1 and a detection limit of 0.14 ?M. Luminescence experiments show that 1 has high selectivity and sensitivity to MnO4 - in other anions. Its quenching efficiency (K sv) is 5.54 × 103 M-1, and the detection limit is 0.29 ?M.

SUBMITTER: Qian J

PROVIDER: S-EPMC6682116 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature

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Macromolecular Probe Based on a NiII/TbIII Coordination Polymer for Sensitive Recognition of Human Serum Albumin (HSA) and MnO4.

Qian Jing J Sun Mei-Mei MM Liu Ming M Gu Wen W

ACS omega 20190710 7

Reported here are the design and fluorescence characters of a NiII/TbIII polymer, [Tb2Ni3(HCAM)6(H2O)12] n (1) (H3CAM = chelidamic acid). Under physiological conditions, the binding of biocompatible water soluble 1 to human serum albumin (HSA) was studied by spectroscopy techniques, which revealed that 1 could inherent the fluorescent light of HSA in a static quencher co ...[more]

PMID: 31460306

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Project description:Transition metal oxides are characterized by an acute structure and composition dependent electrocatalytic activity toward the oxygen evolution (OER) and oxygen reduction (ORR) reactions. For instance, Mn containing oxides are among the most active ORR catalysts, while Ni based compounds tend to show high activity toward the OER in alkaline solutions. In this study, we show that incorporation of Ni into α-MnO2, by adding Ni precursor into the Mn-containing hydrothermal solution, can generate distinctive sites with different electronic configurations and contrasting electrocatalytic activity. The structure and composition of the Ni modified hollandite α-MnO2 phase were investigated by X-ray absorption spectroscopy (XAS), X-ray diffraction (XRD), transmission electron microscopy coupled to energy-dispersive X-ray spectroscopy (TEM-EDX), inductively coupled plasma-optical emission spectroscopy (ICP-OES), and X-ray photoelectron spectroscopy (XPS). Our analysis suggests that Mn replacement by Ni into the α-MnO2 lattice (site A) occurs up to approximately 5% of the total Mn content, while further increasing Ni content promotes the nucleation of separate Ni phases (site B). XAS and XRD show that the introduction of sites A and B have a negligible effect on the overall Mn oxidation state and bonding characteristics, while very subtle changes in the XPS spectra appear to suggest changes in the electronic configuration upon Ni incorporation into the α-MnO2 lattice. On the other hand, changes in the electronic structure promoted by site A have a significant impact in the pseudocapacitive responses obtained by cyclic voltammetry in KOH solution at pH 13, revealing the appearance of Mn 3d orbitals at the energy (potential) range relevant to the ORR. The evolution of Mn 3d upon Ni replacement significantly increases the catalytic activity of α-MnO2 toward the ORR. Interestingly, the formation of segregated Ni phases (site B) leads to a decrease in the ORR activity while increasing the OER rate.

Dataset Information

Macromolecular Probe Based on a NiII/TbIII Coordination Polymer for Sensitive Recognition of Human Serum Albumin (HSA) and MnO4.

Publications

Macromolecular Probe Based on a Ni<sup>II</sup>/Tb<sup>III</sup> Coordination Polymer for Sensitive Recognition of Human Serum Albumin (HSA) and MnO<sub>4</sub>.

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