Ontology highlight
ABSTRACT:
SUBMITTER: Li Y
PROVIDER: S-EPMC6683128 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Li Yansong Y Wang Zixiang Z Boileau Isabelle I Dreher Jean-Claude JC Gelskov Sofie S Genauck Alexander A Joutsa Juho J Kaasinen Valtteri V Perales José C JC Romanczuk-Seiferth Nina N Ruiz de Lara Cristian M CM Siebner Hartwig R HR van Holst Ruth J RJ van Timmeren Tim T Sescousse Guillaume G
Translational psychiatry 20190805 1
Gambling disorder is a serious psychiatric condition characterized by decision-making and reward processing impairments that are associated with dysfunctional brain activity in the orbitofrontal cortex (OFC). However, it remains unclear whether OFC functional abnormalities in gambling disorder are accompanied by structural abnormalities. We addressed this question by examining the organization of sulci and gyri in the OFC. This organization is in place very early and stable across life, such tha ...[more]