Ontology highlight
ABSTRACT:
SUBMITTER: Mortensen R
PROVIDER: S-EPMC6683187 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Communications biology 20190805
Tuberculosis, caused by infection with <i>Mycobacterium tuberculosis</i> (Mtb), kills over 1.6 million people each year despite availability of antibiotics. The increase in drug resistant Mtb strains is a major public health emergency and host-directed therapy as adjunct to antibiotic treatment has gained increased interest. Cyclooxygenase inhibitors (COXi) are frequently used drugs to alleviate tuberculosis related symptoms. Mouse studies of acute intravenous Mtb infection have suggested a pote ...[more]