Dataset Information

Retrospective cohort study on factors associated with mortality in high-risk pediatric critical care patients in the Netherlands.

ABSTRACT:

Background

High-risk patients in the pediatric intensive care unit (PICU) contribute substantially to PICU-mortality. Complex chronic conditions (CCCs) are associated with death. However, it is unknown whether CCCs also increase mortality in the high-risk PICU-patient. The objective of this study is to determine if CCCs or other factors are associated with mortality in this group.

Methods

Retrospective cohort study from a national PICU-database (2006-2012, n?=?30,778). High-risk PICU-patients, defined as patients ?30% according to either the recalibrated Pediatric Risk of Mortality-II (PRISM) or the Paediatric Index of Mortality 2 (PIM2), were included. Patients with a cardiac arrest before PICU-admission were excluded.

Results

In total, 492 high-risk PICU patients with mean predicted risk of 24.8% (SD 22.8%) according to recalibrated PIM2 and 40.0% (SD 23.8%) according to recalibrated PRISM were included of which 39.6% died. No association was found between CCCs and non-survival (odds ratio 0.99; 95% CI 0.62-1.59). Higher Glasgow coma scale at PICU admission was associated with lower mortality (odds ratio 0.91; 95% CI 0.87-0.96).

Conclusions

Complex chronic conditions are not associated with mortality in high-risk PICU patients.

SUBMITTER: Verlaat CW

PROVIDER: S-EPMC6683538 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature

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Publications

Retrospective cohort study on factors associated with mortality in high-risk pediatric critical care patients in the Netherlands.

Verlaat Carin W CW Wubben Nina N Visser Idse H IH Hazelzet Jan A JA van der Hoeven Johannes J Lemson Joris J van den Boogaard Mark M

BMC pediatrics 20190806 1

<h4>Background</h4>High-risk patients in the pediatric intensive care unit (PICU) contribute substantially to PICU-mortality. Complex chronic conditions (CCCs) are associated with death. However, it is unknown whether CCCs also increase mortality in the high-risk PICU-patient. The objective of this study is to determine if CCCs or other factors are associated with mortality in this group.<h4>Methods</h4>Retrospective cohort study from a national PICU-database (2006-2012, n = 30,778). High-risk P ...[more]

PMID: 31387556

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Dataset Information

Retrospective cohort study on factors associated with mortality in high-risk pediatric critical care patients in the Netherlands.

Background

Methods

Results

Conclusions

Publications

Retrospective cohort study on factors associated with mortality in high-risk pediatric critical care patients in the Netherlands.

Similar Datasets

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